Registry Study on Epidemiological and Biological Disease Profile as Well as Clinical Outcome in Patients With Low Grade Gliomas

Rekrutierend

NCT-Nummer:
NCT02686229

Studienbeginn:
November 2015

Letztes Update:
11.05.2023

Wirkstoff:
-

Indikation (Clinical Trials):
Glioma

Geschlecht:
Alle

Altersgruppe:
Erwachsene (18+)

Phase:
-

Sponsor:
University of Ulm

Collaborator:
Charite University, Berlin, Germany

Kontakt

Jan Coburge, MD
Kontakt:
Phone: 082219628858
E-Mail: jan.coburger@uni-ulm.de» Kontaktdaten anzeigen

Studienlocations
(1 von 1)

University of Ulm
Ulm
(Baden-Württemberg)
GermanyRekrutierend» Google-Maps
Ansprechpartner:
Jan Coburger, MD
E-Mail: jan.coburger@uni-ulm.de» Ansprechpartner anzeigen

Studien-Informationen

Brief Summary:

The LoG-Glio-Registry is based on a network of german hospitals gathering radiological,

clinical, epidemiological and molecular data on all patients diagnosed with a low grade

glioma.

Ein-/Ausschlusskriterien

Inclusion Criteria:

- Patients with radiological suspected diagnosis of a low grade glioma

- Age ≥ 18 years. There is no upper age limit.

Exclusion Criteria:

- Severe neurological or psychiatric disorder interfering with ability to give an

informed consent

- No consent for registration, storage and processing of the individual disease

characteristics and course as well as information of the family physician about study

participation

- No consent for bio-banking of patient's biological specimens and performance of

analyses on stored material.

Studien-Rationale

Primary outcome:

1. Progression-free survival (PFS) (Time Frame - 5yrs)

2. Overall survival (OS) (Time Frame - 15yrs)

Secondary outcome:

1. Extent of tumor resection (Time Frame - 3yrs):
calculated based on volumetric assessement of tumor in cm³ and residual tumor in pre and postoperative MRI

2. Quality of life (QoL) assessed by the EORTC QLQ C-30/BN-20. (European Organisation for Research and Treatment of Cancer Quality of Life Questionaire C-30 (Time Frame - 5yrs)

Geprüfte Regime

no interventions

Quelle: ClinicalTrials.gov