SwissNET - a Registry for Neuroendocrine Tumours in Switzerland
NCT-Nummer:
NCT01039922
Studienbeginn:
Januar 2008
Letztes Update:
23.01.2020
Wirkstoff:
-
Indikation (Clinical Trials):
Neoplasms, Neuroendocrine Tumors, Carcinoid Tumor
Geschlecht:
Alle
Altersgruppe:
Alle
Phase:
-
Sponsor:
University Hospital Inselspital, Berne
Collaborator:
Cantonal Hospital of St. Gallen, University Hospital, Basel, Switzerland, University Hospital, Geneva, University of Lausanne Hospitals, University Hospital, Zürich, Triemlispital Zurich, Spitalnetz Bern, Ente Ospedaliero Cantonale, Bellinzona, Luzerner Kantonssp
Studienleiter
Study Director
Institute of Pathology, University of Bern, Bern
Kontakt
Kontakt:
Phone: ++41 44 255 2214
E-Mail: Alexander.Siebenhuener@usz.ch» Kontaktdaten anzeigen
Kontakt:
Phone: ++41 31 632 40 70
E-Mail: emanuel.christ@insel.ch» Kontaktdaten anzeigen
Studienlocations
(3 von 55)
Aarau
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Aarberg
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Affoltern am Albis
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Altdorf
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Basel
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Basel
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Bellinzona
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3010 Bern
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Bern
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Bern
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Biel
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Bruderholz
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Burgdorf
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Churwalden
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Chur
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Delémont
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Dornach
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Einsiedeln
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Geneva
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Grabs
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Horgen
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Horgen
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Interlaken
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Lachen
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Langenthal
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Laufen
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Lausanne
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Liestal
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Luzern
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Luzern
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Luzern
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Männedorf
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Münsterlingen
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Olten
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Rheinfelden
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Sarnen
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Schlieren
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Schwyz
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Seuzach
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Sion
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Solothurn
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St. Gallen
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Stans
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Thun
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Uster
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Visp
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Winterthur
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Wolhusen
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Zollikerberg
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Zug
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Zweisimmen
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Zürich
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Zürich
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Zürich
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Zürich
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Studien-Informationen
Detailed Description:Background
Gastroentero-pancreatic neuroendocrine tumours (GEP-NETs) are generally classified as rare diseases. Little is known about their cell biology and their mechanistic regulation. During the last years, the incidence of GEP-NETs is continuously increasing worldwide. In parallel, novel treatment options are currently evaluated which may substantially improve prognosis of patients with NETs. Data on such tumours in Switzerland, however, is scarce and treatment strategies vary throughout the country.
Objective
To systematically and prospectively collect clinical information of patients with GEP-NETs in Switzerland based on a histologically confirmed diagnosis.
Methods
All NETs of both, gastrointestinal and pulmonary origin are included provided that patients have given informed consent. Data will be entered prospectively and anonymised in a specifically designed database. Contributing centres and general practitioners are visited by a study nurse, patient files are analysed and data is transferred to the database. In case of conflicting evidence, questions are resolved in collaboration with a review board of SwissNET. Evaluation of treatment modalities and patient outcomes (e.g. mortality, hospitalisation rate) will take place within regular time frames.
Ein-/Ausschlusskriterien
Inclusion Criteria:- Neuroendocrine tumor irrespective of primary tumor location
- Diagnosis in Switzerland
- Given informed consent
Studien-Rationale
Primary outcome:1. Tumor-related mortality (Time Frame - Every 5 years)
Secondary outcome:
1. Incidence of GEP-NET in Switzerland (Time Frame - Every 5 years)
2. Effect of specific treatment strategies (Time Frame - Every 5 years)
Quelle: ClinicalTrials.gov